Genetic Basis of Response of Ghanaian Local Chickens to Infection With a Lentogenic Newcastle Disease Virus

Immune response of chickens to four lentogenic strains of Newcastle disease virus propagated in lamb kidney cell cultures

Experimental Infection of Turkeys with A Virulent Newcastle Disease Virus Isolated from Broiler Chickens

Newcastle disease (ND) is a highly contagious infection of many avian species, mainly chickens and turkeys, with a devastating impact on worldwide poultry production. The ND accounts for heavy losses in Iranian poultry flocks. There are some reports regarding the epidemiology of this infection in Iran. This study was performed to investigate the infection of turkeys with a Newcastle disea...

The response of ducks to V4 Newcastle disease virus and its transmission to contact ducks and domestic chickens

Experimental infection of Muscovy ducks with V4 strain of Newcastle disease virus was undertaken to determine the response of the ducks to the virus and the possibility of virus transmission to ducks and chickens in village like conditions. Twelve ducks were randomly and equally divided into three groups of control, inoculated and in-contact. Additionally, the chickens were placed into two grou...

Induction of Intestinal Immune Response to Lentogenic Vaccine Strain of Newcastle Disease Virus in Chicken

Mucosal surface provide portal entry for a majority of infectious agents. Hence, protection at the mucosal surface through immunization plays an important role in containing its systemic spread. Mucosal vaccination of chicken at early stages of life with live attenuated strain of Newcastle disease virus (NDV) induces both cellular and humoral immune responses against the Newcastle disease. In o...

Generation of recombinant lentogenic Newcastle disease virus from cDNA.

Recombinant lentogenic Newcastle disease virus (NDV) of the vaccine strain Clone-30 was reproducibly generated after simultaneous expression of antigenome-sense NDV RNA and NDV nucleoprotein, phosphoprotein and RNA-dependent RNA polymerase from plasmids transfected into cells stably expressing T7 RNA polymerase. For this purpose, the genome of Clone-30, comprising 15186 nt, was cloned and seque...